PTY to MDE

Panama City to Medellin flight ticket price

Compare fares, departure times, stops and baggage details for this route, then open the full search when you are ready to check current availability and complete booking.

PTY
Panama City (PTY), PanamaTocumen International
MDE
Medellin (MDE), ColombiaJose Maria Cordova
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Live flights for Sat, 06 Jun 2026

Review fares, stops, timings and baggage. Use Search or View all flights for the complete search result.

Showing flight options for the selected travel date.
Currency: USD
Sat, 06 JunPTY to MDE$678 Sun, 07 JunPTY to MDE Mon, 08 JunPTY to MDE Tue, 09 JunPTY to MDE Wed, 10 JunPTY to MDE Thu, 11 JunPTY to MDE Fri, 12 JunPTY to MDE
Sort By:DepartureDurationArrivalPrice
American Airlines
American Airlines
AA-960
13:15
2026-06-06
Panama City (PTY)PanamaTocumen International
10H :35 M
1 Stop
MIA · 4h 03mMiami (MIA), United States
23:50
2026-06-06
Medellin (MDE)ColombiaJose Maria Cordova
$678
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-960
13:15
2026-06-06
Panama City (PTY)PanamaTocumen International
23H :36 M
1 Stop
MIA · 16h 52mMiami (MIA), United States
12:51
2026-06-07
Medellin (MDE)ColombiaJose Maria Cordova
$715
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1033
15:30
2026-06-06
Panama City (PTY)PanamaTocumen International
29H :40 M
1 Stop
IAH · 20h 20mHouston (IAH), United States
21:10
2026-06-07
Medellin (MDE)ColombiaJose Maria Cordova
$1,879
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1249
07:55
2026-06-06
Panama City (PTY)PanamaTocumen International
13H :15 M
1 Stop
IAH · 4h 05mHouston (IAH), United States
21:10
2026-06-06
Medellin (MDE)ColombiaJose Maria Cordova
$1,987
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1031
10:00
2026-06-06
Panama City (PTY)PanamaTocumen International
11H :10 M
1 Stop
IAH · 2h 00mHouston (IAH), United States
21:10
2026-06-06
Medellin (MDE)ColombiaJose Maria Cordova
$1,987
total fare
Non Refundable 8 Seat Left Economy
Cabin: Included
Air Europa
Air Europa
UX-56
20:25
2026-06-06
Panama City (PTY)PanamaTocumen International
22H :10 M
1 Stop
MAD · 2h 10mMadrid (MAD), Spain
18:35
2026-06-07
Medellin (MDE)ColombiaJose Maria Cordova
$4,559
total fare
Refundable 9 Seat Left Economy
Cabin: Included

Recommended hotels in Medellin

Stay options near the arrival city for the same travel date.

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Hotel Florida Nueva
3.0Very GoodLive availability

Hotel Florida Nueva

- CARRERA 70 45E 85 Medellin CO,

Free WiFiACBreakfast
Room availability is checked live
$24per night+ taxes if applicable

1 Night • 3 Star

AYENDA 1250 PERLATTO
3.0Very GoodLive availability

AYENDA 1250 PERLATTO

- Cl. 52 ##47-70, Bello, Antioquia, Colombia Medellin Colombia,

Free WiFiACBreakfast
Room availability is checked live
$25per night+ taxes if applicable

1 Night • 3 Star

Ofix Hotel
4.0Very GoodLive availability

Ofix Hotel

- Calle 44 #79-86 Calle 44 #79-86 Medellin Colombia,

Free WiFiACBreakfast
Room availability is checked live
$25per night+ taxes if applicable

1 Night • 4 Star

Hotel Romanza
3.0Very GoodLive availability

Hotel Romanza

- Carrera 45 46-43 50016 Medellin Colombia,

Free WiFiACBreakfast
Room availability is checked live
$26per night+ taxes if applicable

1 Night • 3 Star

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Fare highlights

Selected flight highlights for 06 Jun 2026.

Open full search
Lowest fare $678 American Airlines 13:15
Earliest departure $1,987 United Airlines 07:55
Shortest duration $678 American Airlines 13:15
Night 00:00-05:59 No option Open full search for more
Morning 06:00-11:59 $1,987 United Airlines at 07:55
Afternoon 12:00-17:59 $678 American Airlines at 13:15
Evening 18:00-23:59 $4,559 Air Europa at 20:25

Panama City to Medellin route details

Panama City (PTY)

Tocumen International

Panama

GMT -5

Latitude: 9.0713596344

Longitude: -79.3834991455

Medellin (MDE)

Jose Maria Cordova

Colombia

GMT -5

Latitude: 6.16454

Longitude: -75.4231

Distance: Panama City (PTY), Panama to Medellin (MDE), Colombia - 543.10 km
Flights shown for 06 Jun 2026. View all flights opens the complete search result.

Panama City to Medellin - what to expect when booking

The PTY to MDE cards above show selected flight options. Airline prices and seat availability can move quickly, so the final fare is rechecked in the booking flow.

Approx route distance: 543.10 km.

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More flights from Panama City (PTY)24 routes
Panama City → Amsterdam
PTY → AMS
Panama City → Asuncion
PTY → ASU
Panama City → Atlanta
PTY → ATL
Panama City → Barcelona
PTY → BLA
Panama City → Barranquilla
PTY → BAQ
Panama City → Belo Horizonte
PTY → CNF
Panama City → Bogota
PTY → BOG
Panama City → Boston
PTY → BOS
Panama City → Brasilia
PTY → BSB
Panama City → Bucaramanga
PTY → BGA
Panama City → Buenos Aires
PTY → EZE
Panama City → Cali
PTY → CLO
Panama City → Cancun
PTY → CUN
Panama City → Maiquetia
PTY → CCS
Panama City → Cartagena
PTY → CTG
Panama City → Cucuta
PTY → CUC
Panama City → Chicago
PTY → ORD
Panama City → Cordoba
PTY → COR
Panama City → Curacao
PTY → CUR
Panama City → Fort Lauderdale
PTY → FLL
Panama City → Dallas
PTY → DFW
Panama City → Guadalajara
PTY → GDL
Panama City → Guatemala City
PTY → GUA
Panama City → Guayaquil
PTY → GYE
More flights from Medellin (MDE)18 routes
Medellin → Barranquilla
MDE → BAQ
Medellin → Bogota
MDE → BOG
Medellin → Bucaramanga
MDE → BGA
Medellin → Cali
MDE → CLO
Medellin → Maiquetia
MDE → CCS
Medellin → Cartagena
MDE → CTG
Medellin → Cucuta
MDE → CUC
Medellin → Curacao
MDE → CUR
Medellin → Fort Lauderdale
MDE → FLL
Medellin → Lima
MDE → LIM
Medellin → Madrid
MDE → MAD
Medellin → Miami
MDE → MIA
Medellin → New York
MDE → JFK
Medellin → Panama City
MDE → PTY
Medellin → Quito
MDE → UIO
Medellin → San Andres Island
MDE → ADZ
Medellin → San Salvador
MDE → SAL
Medellin → Santa Marta
MDE → SMR
Frequently asked questions - Panama City to Medellin flights
Generally yes. When your travel date is fixed, comparing live fares early gives you better visibility of timings, baggage and fare rules before prices change.
The approximate route distance between Panama City (PTY) and Medellin (MDE) is 543.10 km. Actual flying distance can vary by airline routing.
Availability changes by airline schedule and date. Use the Stops filter to quickly check non-stop, one-stop and connecting options on this landing page.
Airline inventory can change within minutes. Book Now sends the selected result to the review flow where the fare is checked again before final booking.
Yes. The date strip and search box open the full search for the selected date, while this page keeps the route details easy to compare.