MSP to TYS

Minneapolis to Knoxville flight ticket price

Compare fares, departure times, stops and baggage details for this route, then open the full search when you are ready to check current availability and complete booking.

MSP
Minneapolis (MSP), United StatesMinneapolis - St. Paul Intl
TYS
Knoxville (TYS), United StatesMc Ghee Tyson
Search

Live flights for Sat, 06 Jun 2026

Review fares, stops, timings and baggage. Use Search or View all flights for the complete search result.

Showing flight options for the selected travel date.
Currency: USD
Sat, 06 JunMSP to TYS$513 Sun, 07 JunMSP to TYS Mon, 08 JunMSP to TYS Tue, 09 JunMSP to TYS Wed, 10 JunMSP to TYS Thu, 11 JunMSP to TYS Fri, 12 JunMSP to TYS
Sort By:DepartureDurationArrivalPrice
Delta Air Lines
Delta Air Lines
DL-5527
19:45
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
2H :12 M
Non Stop
22:57
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$513
total fare
Non Refundable 8 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-894
06:00
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :26 M
1 Stop
CLT · 1h 25mCharlotte (CLT), United States
12:26
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-2150
06:00
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
6H :02 M
1 Stop
DFW · 1h 10mDallas (DFW), United States
13:02
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-5488
06:02
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
6H :11 M
1 Stop
PHL · 1h 15mPhiladelphia (PHL), United States
13:13
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-4803
06:08
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :25 M
1 Stop
ORD · 1h 40mChicago (ORD), United States
12:33
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1039
07:03
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :45 M
1 Stop
ATL · 2h 28mAtlanta (ATL), United States
13:48
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-1395
08:01
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
7H :42 M
1 Stop
DFW · 2h 53mDallas (DFW), United States
16:43
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1891
09:00
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :53 M
1 Stop
DEN · 0h 42mDenver (DEN), United States
15:53
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 4 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-2152
10:36
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
7H :55 M
1 Stop
DFW · 3h 10mDallas (DFW), United States
19:31
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-2154
10:45
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :52 M
1 Stop
CLT · 1h 49mCharlotte (CLT), United States
17:37
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-2154
10:45
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
7H :48 M
1 Stop
CLT · 3h 48mCharlotte (CLT), United States
19:33
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1305
13:36
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
7H :43 M
1 Stop
DEN · 2h 37mDenver (DEN), United States
22:19
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 4 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1531
15:17
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
4H :39 M
1 Stop
ORD · 1h 07mChicago (ORD), United States
20:56
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 3 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1036
15:37
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
7H :24 M
1 Stop
ATL · 3h 57mAtlanta (ATL), United States
00:01
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1476
15:55
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
4H :30 M
1 Stop
DTW · 1h 11mDetroit (DTW), United States
21:25
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1028
16:58
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
6H :03 M
1 Stop
ATL · 2h 30mAtlanta (ATL), United States
00:01
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-4483
17:34
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :15 M
1 Stop
ORD · 1h 27mChicago (ORD), United States
23:49
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 5 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-2151
17:43
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
5H :04 M
1 Stop
CLT · 1h 06mCharlotte (CLT), United States
23:47
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1026
18:12
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
4H :49 M
1 Stop
ATL · 1h 12mAtlanta (ATL), United States
00:01
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-758
07:34
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
4H :44 M
1 Stop
ORD · 1h 11mChicago (ORD), United States
13:18
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$605
total fare
Non Refundable 2 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-307
06:00
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
26H :43 M
1 Stop
ORD · 23h 11mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$643
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-758
07:34
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
25H :09 M
1 Stop
ORD · 21h 37mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$643
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included

Recommended hotels in Knoxville

Stay options near the arrival city for the same travel date.

Search hotels
Days Inn by Wyndham Knoxville East
3.0Very GoodLive availability

Days Inn by Wyndham Knoxville East

- 5423 Asheville Hwy, Knoxville, TN 37914 ,

Free WiFiACBreakfast
Room availability is checked live
$73per night+ taxes if applicable

1 Night • 3 Star

Pigeon Forge Hotel
3.0Very GoodLive availability

Pigeon Forge Hotel

- 2179 Parkway 37863 Pigeon Forge Tennessee United States,

Free WiFiACBreakfast
Room availability is checked live
$81per night+ taxes if applicable

1 Night • 3 Star

Vista Suites Pigeon Forge TN
3.0Very GoodLive availability

Vista Suites Pigeon Forge TN

- 2423 Teaster Lane 37863 Pigeon Forge Tennessee United States,

Free WiFiACBreakfast
Room availability is checked live
$87per night+ taxes if applicable

1 Night • 3 Star

WoodSpring Suites Knoxville West
3.0Very GoodLive availability

WoodSpring Suites Knoxville West

- 320 N. Gallaher View Rd. 37923 Knoxville (TN) USA,

Free WiFiACBreakfast
Room availability is checked live
$88per night+ taxes if applicable

1 Night • 3 Star

United Airlines
United Airlines
UA-1531
15:17
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
17H :26 M
1 Stop
ORD · 13h 55mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$643
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-5885
18:53
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
13H :50 M
1 Stop
ORD · 10h 15mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$643
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-5885
18:53
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
25H :03 M
1 Stop
ORD · 21h 27mChicago (ORD), United States
20:56
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$643
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-4483
17:34
2026-06-06
Minneapolis (MSP)United StatesMinneapolis - St. Paul Intl
16H :24 M
1 Stop
ORD · 12h 33mChicago (ORD), United States
10:58
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$678
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
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Fare highlights

Selected flight highlights for 06 Jun 2026.

Open full search
Lowest fare $513 Delta Air Lines 19:45
Earliest departure $523 American Airlines 06:00
Shortest duration $513 Delta Air Lines 19:45
Night 00:00-05:59 No option Open full search for more
Morning 06:00-11:59 $523 American Airlines at 06:00
Afternoon 12:00-17:59 $523 United Airlines at 13:36
Evening 18:00-23:59 $513 Delta Air Lines at 19:45

Minneapolis to Knoxville route details

Minneapolis (MSP)

Minneapolis - St. Paul Intl

United States

GMT -6

Latitude: 44.882

Longitude: -93.221802

Knoxville (TYS)

Mc Ghee Tyson

United States

GMT -5

Latitude: 35.81100082

Longitude: -83.9940033

Distance: Minneapolis (MSP), United States to Knoxville (TYS), United States - 1,274.49 km
Flights shown for 06 Jun 2026. View all flights opens the complete search result.

Minneapolis to Knoxville - what to expect when booking

The MSP to TYS cards above show selected flight options. Airline prices and seat availability can move quickly, so the final fare is rechecked in the booking flow.

Approx route distance: 1,274.49 km.

Before you book

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More flights from Minneapolis (MSP)24 routes
Minneapolis → Aberdeen
MSP → ABR
Minneapolis → Albany
MSP → ALB
Minneapolis → Albuquerque
MSP → ABQ
Minneapolis → Alpena
MSP → APN
Minneapolis → Amsterdam
MSP → AMS
Minneapolis → Anchorage
MSP → ANC
Minneapolis → Appleton
MSP → ATW
Minneapolis → Atlanta
MSP → ATL
Minneapolis → Austin
MSP → AUS
Minneapolis → Bemidji
MSP → BJI
Minneapolis → Fayetteville
MSP → XNA
Minneapolis → Billings
MSP → BIL
Minneapolis → Birmingham
MSP → BHM
Minneapolis → Bismarck
MSP → BIS
Minneapolis → Bloomington-Normal
MSP → BMI
Minneapolis → Boise
MSP → BOI
Minneapolis → Boston
MSP → BOS
Minneapolis → Bozeman
MSP → BZN
Minneapolis → Brainerd
MSP → BRD
Minneapolis → Buffalo Ny
MSP → BUF
Minneapolis → Calgary
MSP → YYC
Minneapolis → Cancun
MSP → CUN
Minneapolis → Cedar Rapids
MSP → CID
Minneapolis → Charlotte
MSP → CLT
More flights from Knoxville (TYS)15 routes
Knoxville → Atlanta
TYS → ATL
Knoxville → Charlotte
TYS → CLT
Knoxville → Chicago
TYS → ORD
Knoxville → Denver
TYS → DEN
Knoxville → Detroit Mi
TYS → DTW
Knoxville → Fort Lauderdale
TYS → FLL
Knoxville → Dallas
TYS → DFW
Knoxville → Houston
TYS → IAH
Knoxville → Minneapolis
TYS → MSP
Knoxville → New York
TYS → LGA
Knoxville → Philadelphia
TYS → PHL
Knoxville → Punta Gorda
TYS → PGD
Knoxville → Sanford
TYS → SFB
Knoxville → Clearwater
TYS → PIE
Knoxville → Washington Dulles
TYS → IAD
Frequently asked questions - Minneapolis to Knoxville flights
Generally yes. When your travel date is fixed, comparing live fares early gives you better visibility of timings, baggage and fare rules before prices change.
The approximate route distance between Minneapolis (MSP) and Knoxville (TYS) is 1,274.49 km. Actual flying distance can vary by airline routing.
Availability changes by airline schedule and date. Use the Stops filter to quickly check non-stop, one-stop and connecting options on this landing page.
Airline inventory can change within minutes. Book Now sends the selected result to the review flow where the fare is checked again before final booking.
Yes. The date strip and search box open the full search for the selected date, while this page keeps the route details easy to compare.