DTW to TYS

Detroit Mi to Knoxville flight ticket price

Compare fares, departure times, stops and baggage details for this route, then open the full search when you are ready to check current availability and complete booking.

DTW
Detroit Mi (DTW), United StatesDetroit Metropolitan Wayne County
TYS
Knoxville (TYS), United StatesMc Ghee Tyson
Search

Live flights for Sat, 06 Jun 2026

Review fares, stops, timings and baggage. Use Search or View all flights for the complete search result.

Showing flight options for the selected travel date.
Currency: USD
Sat, 06 JunDTW to TYS$478 Sun, 07 JunDTW to TYS Mon, 08 JunDTW to TYS Tue, 09 JunDTW to TYS Wed, 10 JunDTW to TYS Thu, 11 JunDTW to TYS Fri, 12 JunDTW to TYS
Sort By:DepartureDurationArrivalPrice
United Airlines
United Airlines
UA-1355
07:05
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
26H :38 M
1 Stop
ORD · 23h 18mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-426
08:50
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
24H :53 M
1 Stop
ORD · 21h 33mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-4800
10:55
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
22H :48 M
1 Stop
ORD · 19h 31mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-5381
14:10
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
19H :33 M
1 Stop
ORD · 16h 08mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-5264
18:20
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
15H :23 M
1 Stop
ORD · 11h 58mChicago (ORD), United States
09:43
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-5264
18:20
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
26H :36 M
1 Stop
ORD · 23h 10mChicago (ORD), United States
20:56
2026-06-07
Knoxville (TYS)United StatesMc Ghee Tyson
$478
total fare
Non Refundable 6 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-5347
08:25
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
1H :39 M
Non Stop
10:04
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$513
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-5138
19:50
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
1H :35 M
Non Stop
21:25
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$513
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-2375
05:20
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :37 M
1 Stop
ATL · 1h 38mAtlanta (ATL), United States
09:57
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-1108
05:37
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
7H :25 M
1 Stop
DFW · 2h 14mDallas (DFW), United States
13:02
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-387
06:00
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :36 M
1 Stop
CLT · 1h 20mCharlotte (CLT), United States
10:36
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-4055
06:00
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :42 M
1 Stop
IAD · 1h 26mWashington (IAD), United States
10:42
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-5170
06:00
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
7H :13 M
1 Stop
PHL · 3h 20mPhiladelphia (PHL), United States
13:13
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-1611
06:15
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
3H :42 M
1 Stop
ATL · 0h 46mAtlanta (ATL), United States
09:57
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-6465
06:45
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :08 M
1 Stop
ORD · 0h 30mChicago (ORD), United States
10:53
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-6465
06:45
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
5H :48 M
1 Stop
ORD · 2h 10mChicago (ORD), United States
12:33
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-1355
07:05
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
6H :13 M
1 Stop
ORD · 2h 52mChicago (ORD), United States
13:18
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 2 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-2294
07:29
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
6H :19 M
1 Stop
ATL · 3h 25mAtlanta (ATL), United States
13:48
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-482
07:47
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
8H :56 M
1 Stop
DFW · 3h 42mDallas (DFW), United States
16:43
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-965
08:30
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
5H :18 M
1 Stop
ATL · 2h 25mAtlanta (ATL), United States
13:48
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-426
08:50
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :28 M
1 Stop
ORD · 1h 07mChicago (ORD), United States
13:18
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 2 Seat Left Economy
Cabin: Included
Delta Air Lines
Delta Air Lines
DL-2777
09:30
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :18 M
1 Stop
ATL · 1h 25mAtlanta (ATL), United States
13:48
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 9 Seat Left Economy
Cabin: Included

Recommended hotels in Knoxville

Stay options near the arrival city for the same travel date.

Search hotels
Econo Lodge Inn & Suites Knoxville East
2.0Very GoodLive availability

Econo Lodge Inn & Suites Knoxville East

- 7424 Strawberry Plains Pk. 7424 Strawberry Plains Pk. 37924 Knoxville (TN) USA,

Free WiFiACBreakfast
Room availability is checked live
$63per night+ taxes if applicable

1 Night • 2 Star

Econo Lodge Knoxville West - Turkey Creek
2.0Very GoodLive availability

Econo Lodge Knoxville West - Turkey Creek

- 500 Lovell Road 37932 Knoxville Tennessee USA,

Free WiFiACBreakfast
Room availability is checked live
$67per night+ taxes if applicable

1 Night • 2 Star

OYO Hotel Knoxville TN Cedar Bluff I-40
2.0Very GoodLive availability

OYO Hotel Knoxville TN Cedar Bluff I-40

- 317 N Cedar Bluff Rd Knoxville 37923 ,

Free WiFiACBreakfast
Room availability is checked live
$74per night+ taxes if applicable

1 Night • 2 Star

Days Inn by Wyndham Pigeon Forge Parkway
2.0Very GoodLive availability

Days Inn by Wyndham Pigeon Forge Parkway

- 4010 Parkway 37863 Pigeon Forge Tennessee United States,

Free WiFiACBreakfast
Room availability is checked live
$75per night+ taxes if applicable

1 Night • 2 Star

American Airlines
American Airlines
AA-1791
10:01
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
5H :14 M
1 Stop
CLT · 1h 59mCharlotte (CLT), United States
15:15
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-5516
10:03
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
5H :46 M
1 Stop
DCA · 2h 14mWashington (DCA), United States
15:49
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
United Airlines
United Airlines
UA-3500
10:13
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
4H :14 M
1 Stop
IAD · 1h 00mWashington (IAD), United States
14:27
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 3 Seat Left Economy
Cabin: Included
American Airlines
American Airlines
AA-1792
12:02
2026-06-06
Detroit MI (DTW)United StatesDetroit Metropolitan Wayne County
7H :29 M
1 Stop
DFW · 2h 23mDallas (DFW), United States
19:31
2026-06-06
Knoxville (TYS)United StatesMc Ghee Tyson
$523
total fare
Non Refundable 7 Seat Left Economy
Cabin: Included
View all flights
No flights match the selected filters. Clear filters or open full search.

Fare highlights

Selected flight highlights for 06 Jun 2026.

Open full search
Lowest fare $478 United Airlines 07:05
Earliest departure $523 Delta Air Lines 05:20
Shortest duration $513 Delta Air Lines 19:50
Night 00:00-05:59 $523 Delta Air Lines at 05:20
Morning 06:00-11:59 $478 United Airlines at 07:05
Afternoon 12:00-17:59 $478 United Airlines at 14:10
Evening 18:00-23:59 $478 United Airlines at 18:20

Detroit Mi to Knoxville route details

Detroit Mi (DTW)

Detroit Metropolitan Wayne County

United States

GMT -5

Latitude: 42.212398529052734

Longitude: -83.35340118408203

Knoxville (TYS)

Mc Ghee Tyson

United States

GMT -5

Latitude: 35.81100082

Longitude: -83.9940033

Distance: Detroit Mi (DTW), United States to Knoxville (TYS), United States - 713.94 km
Flights shown for 06 Jun 2026. View all flights opens the complete search result.

Detroit Mi to Knoxville - what to expect when booking

The DTW to TYS cards above show selected flight options. Airline prices and seat availability can move quickly, so the final fare is rechecked in the booking flow.

Approx route distance: 713.94 km.

Before you book

Compare nearby dates

The date strip opens the complete search result for the route and selected date.

Use filters

Shortlist by price, stops, departure time and refundable fare preference.

Check fare rows

Select expands fare choices on the card before you move to review and booking.

More flights from Detroit Mi (DTW)23 routes
Detroit Mi → Akron/canton
DTW → CAK
Detroit Mi → Albany
DTW → ALB
Detroit Mi → Allentown
DTW → ABE
Detroit Mi → Alpena
DTW → APN
Detroit Mi → Amsterdam
DTW → AMS
Detroit Mi → Appleton
DTW → ATW
Detroit Mi → Fletcher
DTW → AVL
Detroit Mi → Atlanta
DTW → ATL
Detroit Mi → Atlantic City
DTW → ACY
Detroit Mi → Austin
DTW → AUS
Detroit Mi → Bangor
DTW → BGR
Detroit Mi → Beijing
DTW → PEK
Detroit Mi → Fayetteville
DTW → XNA
Detroit Mi → Birmingham
DTW → BHM
Detroit Mi → Bloomington-Normal
DTW → BMI
Detroit Mi → Boston
DTW → BOS
Detroit Mi → Buffalo Ny
DTW → BUF
Detroit Mi → Burlington
DTW → BTV
Detroit Mi → Cancun
DTW → CUN
Detroit Mi → Cedar Rapids
DTW → CID
Detroit Mi → Charleston
DTW → CHS
Detroit Mi → Charlotte
DTW → CLT
Detroit Mi → Chattanooga
DTW → CHA
More flights from Knoxville (TYS)15 routes
Knoxville → Atlanta
TYS → ATL
Knoxville → Charlotte
TYS → CLT
Knoxville → Chicago
TYS → ORD
Knoxville → Denver
TYS → DEN
Knoxville → Detroit Mi
TYS → DTW
Knoxville → Fort Lauderdale
TYS → FLL
Knoxville → Dallas
TYS → DFW
Knoxville → Houston
TYS → IAH
Knoxville → Minneapolis
TYS → MSP
Knoxville → New York
TYS → LGA
Knoxville → Philadelphia
TYS → PHL
Knoxville → Punta Gorda
TYS → PGD
Knoxville → Sanford
TYS → SFB
Knoxville → Clearwater
TYS → PIE
Knoxville → Washington Dulles
TYS → IAD
Frequently asked questions - Detroit Mi to Knoxville flights
Generally yes. When your travel date is fixed, comparing live fares early gives you better visibility of timings, baggage and fare rules before prices change.
The approximate route distance between Detroit Mi (DTW) and Knoxville (TYS) is 713.94 km. Actual flying distance can vary by airline routing.
Availability changes by airline schedule and date. Use the Stops filter to quickly check non-stop, one-stop and connecting options on this landing page.
Airline inventory can change within minutes. Book Now sends the selected result to the review flow where the fare is checked again before final booking.
Yes. The date strip and search box open the full search for the selected date, while this page keeps the route details easy to compare.