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MDW to GSP

Chicago to Greenville Flights

Compare fares, departure times, stops and baggage details for this route, then open the full search when you are ready to check current availability and complete booking.

Fare checked before payment No hidden charges Transparent cancellation policy 24×7 booking support
Lowest fareUS$254Delta Air Lines
Fastest5h 11mgate to gate
Options found19flights on this route
Find your flight MDW GSP

Available Flights & Fares

Compare fares, timings and baggage. Pick the flight that suits your trip.

Prices in USD
19 flight options

Fares are checked again before payment.

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Delta Air Lines
Delta Air Lines
DL-1285
06:05
2026-10-03
Chicago (MDW)United StatesMidway
5H :45 M
1 Stop
ATL · 3h 03m Atlanta (ATL), United States
12:50
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1728
16:30
2026-10-03
Chicago (MDW)United StatesMidway
5H :30 M
1 Stop
ATL · 2h 39m Atlanta (ATL), United States
23:00
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1285
06:05
2026-10-03
Chicago (MDW)United StatesMidway
7H :50 M
1 Stop
ATL · 5h 03m Atlanta (ATL), United States
14:55
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1285
06:05
2026-10-03
Chicago (MDW)United StatesMidway
13H :32 M
1 Stop
ATL · 10h 44m Atlanta (ATL), United States
20:37
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1285
06:05
2026-10-03
Chicago (MDW)United StatesMidway
15H :55 M
1 Stop
ATL · 13h 08m Atlanta (ATL), United States
23:00
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1285
06:05
2026-10-03
Chicago (MDW)United StatesMidway
26H :20 M
1 Stop
ATL · 23h 33m Atlanta (ATL), United States
09:25
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1728
16:30
2026-10-03
Chicago (MDW)United StatesMidway
15H :55 M
1 Stop
ATL · 13h 04m Atlanta (ATL), United States
09:25
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1728
16:30
2026-10-03
Chicago (MDW)United StatesMidway
17H :38 M
1 Stop
ATL · 14h 44m Atlanta (ATL), United States
11:08
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1728
16:30
2026-10-03
Chicago (MDW)United StatesMidway
23H :50 M
1 Stop
ATL · 21h 04m Atlanta (ATL), United States
17:20
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-1728
16:30
2026-10-03
Chicago (MDW)United StatesMidway
26H :20 M
1 Stop
ATL · 23h 29m Atlanta (ATL), United States
19:50
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-2417
11:35
2026-10-03
Chicago (MDW)United StatesMidway
5H :11 M
1 Stop
ATL · 2h 24m Atlanta (ATL), United States
17:46
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-5305
09:29
2026-10-03
Chicago (MDW)United StatesMidway
10H :57 M
1 Stop
DTW · 8h 05m Detroit (DTW), United States
21:26
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-5305
09:29
2026-10-03
Chicago (MDW)United StatesMidway
23H :55 M
1 Stop
DTW · 20h 50m Detroit (DTW), United States
10:24
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-4688
13:19
2026-10-03
Chicago (MDW)United StatesMidway
7H :07 M
1 Stop
DTW · 4h 11m Detroit (DTW), United States
21:26
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-4688
13:19
2026-10-03
Chicago (MDW)United StatesMidway
20H :05 M
1 Stop
DTW · 16h 56m Detroit (DTW), United States
10:24
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-4690
18:40
2026-10-03
Chicago (MDW)United StatesMidway
14H :44 M
1 Stop
DTW · 11h 32m Detroit (DTW), United States
10:24
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-4690
18:40
2026-10-03
Chicago (MDW)United StatesMidway
25H :46 M
1 Stop
DTW · 22h 47m Detroit (DTW), United States
21:26
2026-10-04
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-2417
11:35
2026-10-03
Chicago (MDW)United StatesMidway
8H :02 M
1 Stop
ATL · 5h 15m Atlanta (ATL), United States
20:37
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur
Delta Air Lines
Delta Air Lines
DL-2417
11:35
2026-10-03
Chicago (MDW)United StatesMidway
10H :25 M
1 Stop
ATL · 7h 39m Atlanta (ATL), United States
23:00
2026-10-03
Greenville (GSP)United StatesGreenville-Spartanbur

Recommended hotels in Greenville

Stay options near the arrival city for the same travel date.

Search hotels
Days Inn by Wyndham Greenville
2.0Very GoodLive availability

Days Inn by Wyndham Greenville

946 Fort Dale Rd I-65, Exit 130GreenvilleAlabama 36037 ,

Room availability is checked live
$97per night+ taxes if applicable

1 Night • 2 Star

Comfort Inn Greenville I-65
3.0Very GoodLive availability

Comfort Inn Greenville I-65

1029 Fort Dale Rd, 36037

Room availability is checked live
$109per night+ taxes if applicable

1 Night • 3 Star

Holiday Inn Express Greenville
5.0Very GoodLive availability

Holiday Inn Express Greenville

100 Paul Stabler Dr, 36037

Room availability is checked live
$112per night+ taxes if applicable

1 Night • 5 Star

Days Inn by Wyndham Greenville
2.0Very GoodLive availability

Days Inn by Wyndham Greenville

946 Fort Dale Rd, 36037

Room availability is checked live
$115per night+ taxes if applicable

1 Night • 2 Star

No flights match the selected filters. Clear filters or open full search.

Today's Airfare Highlights

Selected flight highlights for 03 Oct 2026.

Lowest fare $254 Delta Air Lines 06:05
Earliest departure $254 Delta Air Lines 06:05
Shortest duration $459 Delta Air Lines 11:35
Night 00:00-05:59 No option Open full search for more
Morning 06:00-11:59 $254 Delta Air Lines at 06:05
Afternoon 12:00-17:59 $254 Delta Air Lines at 16:30
Evening 18:00-23:59 $528 Delta Air Lines at 18:40

Departure & Arrival Airport Details

Chicago (MDW)

Midway

United States

GMT -6

Latitude: 41.785999

Longitude: -87.752403

Greenville (GSP)

Greenville-Spartanbur

United States

GMT -5

Latitude: 34.8956985474

Longitude: -82.2189025879

Distance: Chicago (MDW), United States to Greenville (GSP), United States - 905.01 km
Flights shown for 03 Oct 2026. View all flights opens the complete search result.
Route forecast

Weather in Chicago and Greenville

Live forecast for both cities, 19 Sep to 22 Sep.

Departure city

Chicago

Tue, 22 Sep
14°CCloudyLow 14°
  • Sat27° / 21°
  • Sun21° / 15°
  • Mon17° / 13°
Arrival city

Greenville

Mon, 21 Sep
24°CRain expectedLow 19°
99% humidity 7 km/h wind 12.6 mm rain
  • Fri31° / 20°
  • Sat33° / 22°
  • Sun31° / 22°

Forecast data from MET Norway, CC BY 4.0.

Smart travel dates

Holidays and peak dates for Greenville

Fares and hotel rates usually run higher around these dates. Booking earlier — or shifting a day or two — often costs less.

Busiest periods: Summer travel (15 Jun – 31 Aug), Holiday season (18 Dec – 02 Jan).

Fixed-date national holidays. Festivals that follow the lunar calendar shift each year and are not listed here — check the exact date for your travel year.

Compare your journey

How to travel Chicago to Greenville

Every option we can actually book for you, compared on price and journey time.

OptionFromJourney timeAvailability
Connecting flight₹24,268Longer — includes a stop19 options

Air distance is about 905 km.

Road distance and coach duration are approximate estimates from the air distance, not a timetable.

Airlines flying from Chicago to Greenville

Compare fares, stops, baggage and refundability across the airlines flying this route.

Delta Air Lines Flights

from $25419 flights
Fares from
$254
Non-stop
None in these results
Departures
19 — compare timings in the list above

Route Overview & Flight Facts

Fastest flight duration5h 11m · Delta Air Lines
First departure of the day06:05 · Delta Air Lines
Last departure of the day18:40 · Delta Air Lines
Options in this snapshot19
Airport codesChicago–MDW, Greenville–GSP

Fares and timings are indicative — the exact price is confirmed with the airline when you search.

Flight Schedule, Timings & Airfare Insights

Daily Flight Schedule & Travel Duration

Around 19 flights appear in the dated route snapshot. Departures run through the day — the first flight leaves around 06:05 and the last around 18:40. The fastest flight takes about 5h 11m.

Morning vs Evening Departure Fares

Lowest fare by departure window: Morning from $254, Afternoon from $254, Evening from $528. These observations do not predict the cheapest departure window on other dates.

Cheapest Airfare & Best Time to Book

Search your travel dates to compare current fares — prices update continuously with airline inventory.

One-Way vs Round-Trip Fare Comparison

Compare the complete cost and conditions of both options for your dates. A round-trip can have different fare and change rules from two one-way tickets. One booking may contain multiple airline PNRs; confirm baggage transfer and connection protection for separate tickets.

Online Web Check-In & Boarding Pass

Check the operating airline’s opening time and check-in deadline for each sector. Seat charges and availability depend on your fare. Use the airline reference and the links on Web Check-in.

How to Book Cheap Flights on FlyX

  1. 1
    Enter your travel details

    Choose one-way or round-trip, pick your dates and travellers in the search form above.

  2. 2
    Compare search results

    Sort or filter the Chicago–Greenville results by price, departure time, stops and airline.

  3. 3
    Open the fare choices

    Check baggage allowance and refundability for each fare type before continuing.

  4. 4
    Review the final price

    Review the refreshed supplier fare, coupon saving and selected payment-method fee before you pay.

  5. 5
    Pay securely

    UPI, cards, net banking and wallets supported; payment and ticket issuance have separate statuses. If issuance is pending, follow the booking status; the confirmed ticket is sent after issuance.

Destination & City Travel Guide

About Chicago

Chicago, the most populous city in Illinois and the third most populous in the United States, is a bustling metropolis known for its iconic skyline, vibrant arts scene, and diverse neighborhoods. Often referred to as the Windy City, Chicago offers a blend of architectural marvels, cultural landmarks, and a dynamic urban atmosphere. From world-class museums to sandy beaches along Lake Michigan, Chicago is a city that captivates visitors with its charm and energy.

Read more about Chicago

Airports

Chicago is served by two major airports:
• O'Hare International Airport (ORD) - Located approximately 18 miles northwest of downtown Chicago
• Chicago Midway International Airport (MDW) - Situated about 10 miles southwest of the city center

Hotels and Restaurants

Chicago offers a wide range of accommodation options to suit every budget:
• The Ritz-Carlton Chicago - Luxury hotel with stunning views of Lake Michigan
• The Drake Hotel - Historic hotel with elegant rooms and top-notch service
• Hotel Lincoln - Boutique hotel with a rooftop bar and quirky decor
• HI Chicago Hostel - Budget-friendly option with modern amenities

When it comes to dining, Chicago is a food lover's paradise:
• Alinea - Renowned for its innovative and artistic dishes
• Lou Malnati's Pizzeria - Famous for its deep-dish pizza
• Girl & the Goat - Popular spot for creative small plates
• Portillo's - Iconic for its Chicago-style hot dogs

Transportation

Getting around Chicago is convenient with various transportation options:
• Chicago Transit Authority (CTA) - Extensive network of buses and 'L' trains
• Metra - Commuter rail system connecting the suburbs to the city
• Taxis and Rideshares - Widely available across the city
• Divvy Bikes - Bike-sharing program with numerous docking stations

Must-See Places

Chicago boasts numerous attractions that should not be missed:
• Millennium Park - Home to the iconic Cloud Gate sculpture (The Bean)
• The Art Institute of Chicago - Houses an impressive collection of artworks
• Navy Pier - Entertainment hub with rides, restaurants, and shops
• Willis Tower Skydeck - Offers breathtaking views from the 103rd floor
• Museum Campus - Includes the Field Museum, Shedd Aquarium, and Adler Planetarium

Climate

Chicago experiences a continental climate with distinct seasons:
• Winter (December to February) - Cold and snowy, ideal for winter sports
• Spring (March to May) - Mild temperatures and blooming flowers
• Summer (June to August) - Warm and humid, perfect for outdoor activities
• Autumn (September to November) - Cool and crisp, great for sightseeing

The best time to visit Chicago is during late spring to early autumn when the weather is pleasant and outdoor events are in full swing. Whether you're exploring its architectural wonders, indulging in its culinary delights, or enjoying its vibrant cultural scene, Chicago promises an unforgettable experience.

Why Book Your Flight with FlyX?

Compare the available Chicago to Greenville options by total price, stops, baggage and fare conditions. Search your dates for current availability, then review traveller details and the final price before paying.

Payment confirmation and ticket issuance are separate steps. If your booking is awaiting a PNR or ticket, follow its status and contact FlyX support when you need help. Your issued ticket contains the airline reference and itinerary. Change and cancellation charges depend on the purchased fare and any separately disclosed service fee.

Fare checked before paymentCoupon eligibility checkedBooking status trackingBooking support

Exclusive Flight Offers & Promo Coupons

Coupon codeOfferMax saving
FLYX20Up to 20% Off on Flights₹1,500

Check coupon eligibility and the final discount on the review page before you pay. View full terms.

Frequently Asked Questions

Is it worth booking Chicago to Greenville flights in advance?

There is no guaranteed cheapest booking window. Compare your planned dates early, check nearby dates and consider baggage, connection time and change conditions as well as price. Across the dates currently loaded for Chicago to Greenville, Saturday shows the lowest fare at $254. That is an observed snapshot for these dates, not a rule that holds every week.

How far is Chicago from Greenville by air?

The direct air distance between Chicago (MDW) and Greenville (GSP) is about 905 km. Actual flight time varies with the routing the airline files and with winds on the day.

Are there non-stop flights from MDW to GSP?

Not for the dates currently loaded - every Chicago to Greenville option showing right now has at least one stop. Non-stop service can differ by season and by day, so it is worth checking nearby dates before you decide.

Which airlines fly Chicago to Greenville?

Delta Air Lines is showing on this route for the dates currently loaded. Fares, baggage allowance and refund rules differ by airline and by fare type, so compare the fare conditions and not only the headline price.

How long is the flight from Chicago to Greenville?

Every option currently loaded has at least one stop, and the shortest total journey time is about 5h 11m including the layover. Non-stop service on this route can vary by season and by day.

What is the cheapest Chicago to Greenville flight fare?

The lowest fare showing on Chicago to Greenville for the dates currently loaded is $254. Fares on the same dates run up to $563, depending on airline, timing and fare type. Airline pricing moves continuously, so treat this as a dated observation rather than a fixed price.

What time do Chicago to Greenville flights depart?

For the dates currently loaded the first departure is around 06:05 and the last is around 18:40, local time at Chicago. Use the departure-time filter on the results above to narrow to a morning, afternoon or evening slot.

Why does the price change after clicking Book Now?

Airline seat inventory and fares change continuously. Selecting Book Now runs a live fare verification with the airline so the price you approve is the price you pay - if it has moved, you see the new figure before any payment.

Before you book this route

Check the airport codes MDW–GSP, local departure and arrival dates, and every connecting airport. Connections can have different document and baggage requirements from your final destination.

Where these fares come from

The fares, durations, stops and baggage shown here come from real airline search results for this route. They are examples for the dates on this page, not a full timetable and not a locked price — run a search to see what is available for your own dates.

Last checked .

Check official travel requirements

Confirm passport, visa and transit rules for your nationality and full itinerary with the relevant government and operating airline. IATA travel-document information explains why requirements vary.

For payment, ticket issuance or a change request, see FlyX support. About FlyX.

United States travel guide for Indian travellers

Planning more than the flight? Our United States guide covers the visa process for Indian passport holders, best time to go, how long to plan for, and which places are worth the days you have. Long-haul city breaks and national parks.

Read the United States travel guide

What to Expect When Booking Your Flight

The MDW to GSP cards above show selected flight options. Airline prices and seat availability can move quickly, so the final fare is rechecked in the booking flow.

Approx route distance: 905.01 km.

Before you book

Compare nearby dates

The date strip opens the complete search result for the route and selected date.

Use filters

Shortlist by price, stops, departure time and refundable fare preference.

Check fare choices

Continue to Booking opens the verified fare choices, including baggage and refundability, before review.

Lowest Chicago to Greenville airfare today, in 30 days and in 90 days

Cheapest Fare Fare Date Airline Departure
Lowest Airfare Today $254 03/10/2026 Delta Air Lines 06:05
Cheapest Airfare Within 30 Days $249 13/10/2026 Delta Air Lines 06:05
Cheapest Airfare Within 90 Days $241 12/12/2026 Delta Air Lines 06:05

Book Chicago to Greenville Flight Tickets on FlyX

Planning to fly from Chicago to Greenville? FlyX lets you compare flight rates, airline timings, layovers, and baggage allowances all in one simple list. From quick non-stop routes to flexible connecting options, finding and booking cheap air tickets has never been easier.

Chicago to Greenville Flight Distance, Duration and Time

The aerial distance between Chicago and Greenville is approximately 905 KM. The flight duration ranges from 5H :11 M up to 26H :20 M depending on whether you book a non-stop flight or a connecting schedule with layovers.

Chicago to Greenville Flight Schedule and Timing

Around 19 flights operate on this route, providing plenty of choices for your travel window. The earliest morning flight departs from Chicago at 06:05, while the last night flight leaves at 18:40. Flights depart from Midway and land at Greenville-Spartanbur.

Flight Route Details & Analysis

Flight Details Information
Route Chicago to Greenville
Aerial Distance 905 KM
Flight Duration 5H :11 M - 26H :20 M
Airport Codes Chicago - MDW, Greenville - GSP
Total Flights Available 19 flights (0 direct)
First Flight Departure Departs at 06:05
Last Flight Departure Departs at 18:40
Early Morning Flights (12 AM - 8 AM) 5 direct/indirect flights
Morning Flights (8 AM - 12 PM) 5 direct/indirect flights
Afternoon Flights (12 PM - 4 PM) 2 direct/indirect flights
Evening Flights (4 PM - 8 PM) 7 direct/indirect flights
Night Flights (8 PM - 12 AM) 0 direct/indirect flights

Airport Information & Terminals

MDW: Chicago airport system. Chicago flights commonly use O'Hare or Midway. O'Hare is a huge hub with rail access; Midway can be easier for some city-side trips. Winter weather and traffic should be part of the booking decision.

GSP: Greenville airport. Greenville airport transfer should be matched to the exact hotel, suburb or meeting area. Rail can work well for light luggage, but late arrivals, winter weather and family baggage often make a direct cab or booked transfer easier.